🩺 Main Uses
Allergy; appetite stimulant; serotonin syndrome (off-label).
🧪 The Science & Facts
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Half‑life (t½)
8 h
How long the drug hangs around. Longer half‑life = slower changes.
Time to Peak (Tmax)
1.5 h
Roughly when you feel the main effect after a dose.
What it hits (receptors)
Primary:
Unique antihistamine with serotonin antagonism → appetite gain.
How your body processes it (metabolism)
Limited CYP metabolism; few interactions.
⚠️ Warnings
- Heavy sedation / grogginess
- May increase appetite and cause weight gain
- Not usually a long-term solution
⏬ Taper & Withdrawal
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If you’re reducing
Not habit-forming; taper not usually needed.
Possible withdrawal
Rebound insomnia/appetite loss possible.
Info here is educational, not medical advice. Always taper with prescriber support if possible.
🧠 Trusted External Sources Last reviewed 22 Aug 2025, 21:34 by Connor O’Driscoll
🔗 Interaction Checker
Always verify drug interactions using the Drugs.com Checker.
Need Help Getting Off This?
Try your GP first. If that doesn't help, find local support services who understand tapering.
Find Support Near You →⚠️ Black Box Warning
None specific, but sedation and anticholinergic burden high.
This is a plain‑English summary of headline safety warnings. Talk to a clinician before changing any medication.