🩺 Main Uses
Major depression (especially with sleep disturbance).
🧪 The Science & Facts
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Half‑life (t½)
2.5 h
How long the drug hangs around. Longer half‑life = slower changes.
Time to Peak (Tmax)
1 h
Roughly when you feel the main effect after a dose.
What it hits (receptors)
Primary:
Improves sleep architecture without typical sedative hangover.
How your body processes it (metabolism)
Improves sleep architecture without typical sedative hangover.
⚠️ Warnings
- Hepatotoxicity risk — requires baseline and periodic LFTs; stop if liver enzymes rise.
⏬ Taper & Withdrawal
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If you’re reducing
No physiological dependence; can stop or taper over 1–2 weeks.
Possible withdrawal
Usually mild (sleep change, headache).
Info here is educational, not medical advice. Always taper with prescriber support if possible.
🧠 Trusted External Sources Last reviewed 22 Aug 2025, 21:12 by Connor O'Driscoll
🔗 Interaction Checker
Always verify drug interactions using the Drugs.com Checker.
Need Help Getting Off This?
Try your GP first. If that doesn't help, find local support services who understand tapering.
Find Support Near You →⚠️ Black Box Warning
Monitor liver function - risk of liver injury.
This is a plain‑English summary of headline safety warnings. Talk to a clinician before changing any medication.